Tretinoin
Retin-ARetinolVesanoid
Skin Care Ingredient
Tretinoin is a type of vitamin A that helps to prevent and treat acne by unclogging pores and reducing inflammation. It also helps to reduce the appearance of fine lines and wrinkles, giving your skin a smoother look.
High Concern
Source: FDA GRAS list
Tretinoin is considered safe when used as directed and under the guidance of a dermatologist, but it can cause skin irritation and sensitivity in some people.
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Last updated: May 16, 2026