Chloromethylisothiazolinone
Preservative
Chloromethylisothiazolinone is a chemical used to prevent the growth of bacteria and mold in products like cosmetics and cleaning supplies. It's often used in combination with other preservatives to keep products fresh for a longer time.
Source: EWG Skin Deep
Chloromethylisothiazolinone has been linked to skin and eye irritation, as well as potential allergic reactions, which is why it's considered a high-risk ingredient.
Contact allergy to products with methylisothiazolinone; plus, topical options for...
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Allergic contact dermatitis in adults with and without atopic dermatitis: Evaluation of the Spanish Contact Dermatitis Registry (REIDAC).
Chicharro P, Munera-Campos M, Zaragoza-Ninet V
2024
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Last updated: May 16, 2026