LabelWise

Acetyl Hexapeptide-3

ArgirelineAcetyl Hexapeptide-8Acetyl Hexapeptide-26

Muscle Relaxant

Acetyl Hexapeptide-3 is a synthetic peptide that helps relax facial muscles, reducing wrinkles and fine lines. It works by blocking the release of a chemical that causes muscles to contract.

Low Concern

Source: FDA GRAS list

Acetyl Hexapeptide-3 is considered safe for use in cosmetics and personal care products, as it has been evaluated by regulatory agencies and found to be non-toxic.

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r/u_skinceuticals

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Development of a Sensory Neuron-Integrated Skin Spheroid Model for the Evaluation of Neuropeptide-Based Topical Delivery Systems.

Martin BA, Viegas J, Dalmolin LF

2025

Read on PubMed

natural wrinkle relaxers

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Last updated: May 16, 2026